GARCINIA COMBOGIA Extract-Medicinal Benefits

What is Garcinia Combogia Fruit?

Garcinia cambogia or Garcinia Gummi-Gutta is a plant and its fruits are usually used as a flavoring agent, food preservative and a food-bulking agent. It can be added to curries and chutneys or it can even be added to soups as a thickening agent. The fruits are generally 5 centimeters in diameter (similar to the size of an orange) with 6 to 8 grooves.

Unripe fruit is green in color. Upon ripening, the fruit turns yellow to orange in color. Appearance wise, it looks very similar to a small pumpkin. It has a slightly sweet and more of a sour flavor and overall it has a very pleasant taste.

When the rinds of this fruit are dried and cured in preparation for storage and extraction, they are dark brown or black in color.

Common Names Of Garcinia Combogia(Kudampuly/Malabar Tamarind)

Garcinia gummi-gutta, formerly known as Garcinia cambogia is native to India and South East Asia.It is commonly called Malabar Tamarind or Pot Tamarind in English, Hila /Velaiti Imli in Hindi, Palam Puli /Koda Puli in Tamil, Kudampuli in Kerala, Malabaru Chinta in Telugu and Uppage in Kannada. The other common names include brindleberry, Gorikapuli,Kankusta, Vrikshamla.

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What is Garcinia Cambogia Extract?

Garcinia cambogia extract is produced by extracting an active principle from its rind, fruit or roots. Solvent is used to release the active compounds present in garcinia cambogia. Extracts are usually made with either glycerin or ethanol (alcohol).

Hydroxycitric acid (active compound)  is extracted from garcinia cambogia fruit and it is usually available in the market in form of supplements (pills).

Garcinia cambogia supplements with HCA are marketed for weight loss.

Medicinal Benefits of Garcinia Cambogia Extract

Garcinia Cambogia is one such plant that contains a wide variety of health promoting compounds. Some of the health promoting chemical compounds includes:

• XANTHONES
• XANTHONE DERIVATIVES
• POLYISOPRENYLATED BENZOPHENONES
• HYDROXYCITRIC ACID (HCA)

Approximately 30% of these compounds are present in the flesh of garcinia cambogia fruit.

Some studies have found that POLYISOPRENYLATED BENZOPHENONES present in garcinia cambogia have anti-HIV and anti-bacterial effect and it also inhibits the action of harmful toxins and thus, protects the cell against damage. Furthermore, it even possesses antibiotic and anti-ulcer activities and modulates gene expression. It also has anti-inflammatory and anti-cancer properties and thus, helps in the treatment of cancer.

Let us see these medicinal benefits of Garcinia Combogia /Kudampuly in detail below:

1.Antioxidant Properties

Extract of garcinia cambogia has the ability to neutralize harmful free radicals and it further inhibited the formation of reactive oxygen species. Thus, it can be said that garcinia cambogia extract prevents the onset of oxidative stress which leads to the the development and progression of various diseases and disorders such as type 2 diabetes mellitus, arthritis, cardiovascular diseases, cancer, cataracts, Alzheimer’s disease and so on.

Such an antioxidant property is due to the presence of hydroxycitric acid, flavonoids and tannins in garcinia cambogia.

2.Antibacterial Properties

Research has found that both garcinia cambogia extract as well as its fruits exhibit anthelmintic properties and throw parasites out of the body. Garcinia cambogia works by inhibiting the mobility of bacteria and parasites and thus, it reduces their action. Higher doses were more effective as an anthelmintic against gastrointestinal worms. Garcinia cambogia fruit and leaves exhibit strong anti-bacterial property against gram positive and gram-negative bacteria.

A recent study showed antibacterial activity of garcinia cambogia fruit against E. coli, S. aures and P. aeruginosa. It killed the cells infected with bacteria and thus, reduced the overall infection.

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3.Garcinia Cambogia for Weight Loss

It is found that garcinia cambogia plays a very important role in weight loss. This property of garcinia cambogia is mainly due to presence of an active component called ‘hydroxycitric acid’ in it.

Hydroxycitric acid inhibits the process of lipogenesis in which carbohydrate in converted to fat in the body. As this conversion is inhibited, body oxidizes carbohydrates and promotes glycogen storage. This in turn suppresses the appetite and thus decreases the body weight gain.

In addition to this, hydroxycitric acid increases the production of serotonin in the brain, which further leads to appetite suppression. Serotonin is a natural appetite suppressant that curbs the hunger cravings and helps in weight loss.

Reducing Type 2 Diabetes Mellitus

Garcinia cambogia extract works on reducing the insulin resistance and improves the peripheral insulin sensitivity. Such effect increases the transport of glucose to cells and muscles and reduces the concentration of glucose and the blood. Thus, it reduces hyperglycemia or high plasma glucose levels.

High visceral fat mass plays an important role in the development of insulin resistance and high plasma glucose levels, thus leading to type 2 diabetes mellitus. Research has shown that garcinia cambogia extract reduces the level of visceral fat, subcutaneous fat as well as total body fat mass. Such a reduction in visceral fat mass reduces the level of insulin resistance

Reducing High Cholesterol & Triglyceride Levels

Garcinia cambogia extract works by inhibiting the activity of ATP lyase, an enzyme that plays a very important role in the manufacture of fat in the body. Such an inhibition reduces the amount of fat in the body and further reduces the formation of cholesterol and triglycerides. It further suppresses the formation of fat in the liver, adipose tissue and intestine.

Antiulcer Properties

Garcinia cambogia extract is very effective in the treatment of gastrointestinal disorders. It soothes the inner lining of the gastrointestinal tract and reduces the inflammation. During gastric ulcer the level of oxidative stress, free radical damage and inflammation increases which further deteriorates the condition. Therefore, it becomes very important to control these levels.

A study showed that garcinia cambogia extract reduced the level of oxidative stress in the gastrointestinal tract and decreased the markers of inflammation. It further inhibited gastric lesion and improved the gastric blood flow. An increase in the blood flow provides more nutrients and oxygen and thus nourishes the gastric area. In addition to this, it also increased the secretion of mucus, a viscous substance that protects the inner lining of the gastrointestinal tract against the harmful action of acid. Garcinia cambogia extract reduces the adhesion of harmful substances to the gastric area and accelerates healing of ulcer.

Anti-Inflammatory Property

Garcinia cambogia extract has a medicine-like effect that reduces the markers of inflammation. Tests showed that treatment with garcinia cambogia extract reduced the gastrointestinal damage and increased the level of antioxidants that further protected against inflammation. It further improved several parameters related to the disease. Thus, garcinia cambogia extract is very useful in the treatment of inflammatory bowel disease.

Excess high fat intake increases the amount of fat in the body, elevates cholesterol level and also leads to increase in the level of inflammation. Adipocytes (cells that store fat) increase the production of pro-inflammatory cytokines and thus increase the overall state of inflammation. The presence of health promoting compounds in garcinia cambogia such as xanthones, flavonoids, and benzophenones possess antioxidant and anti-inflammatory properties. In addition to this, hydroxycitric acid present in garcinia cambogia also reduces inflammation.

Diuretic Activity

One study observed diuretic properties of garcinia cambogia leaf extract in rats. Garcinia cambogia leaf extract produced a diuretic effect and increased the volume of urine output as well as increased the excretion of electrolytes such as sodium, potassium, and chloride. An increase in the level of electrolytes can lead to various disorders, which may be life threatening too. Active principles found in garcinia cambogia leaves that are responsible for its diuretic activity include flavonoids and glycosides. Thus, leaves of garcinia cambogia can be used for the treatment of edema.

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Ayurvedic Uses

In Ayurveda kudampuli is used :

1. To detoxify the body,

2.To treat joint pain

3. To increase bowel movements

4. To treat some uterine problems,

5.Used as carminative and antiseptic.

Other Uses

1. Sun-dried smoked rind of garcinia cambogia is very popular as a spice condiment and is widely used in fish curries.
2. Dried rind of garcinia cambogia fruit when combined with salt can be used to treat fish. This combination is mainly used in India and Sri Lanka. Its dried rind kills the bacteria and thus, improves the shelf life of fish.
3. It is also used as a bulking agent, which makes the meals more filling, and thus, reduces hunger pangs.
4. Due to its high vitamin C content, a tonic is prepared out of garcinia cambogia fruits, which helps to prevent heart diseases.
5. Rind of garcinia cambogia fruit can be used in curries instead of tamarind and lemon.

Precautionary Note

1. If you have any medical condition, ask your doctor or health-care provider before starting with garcinia cambogia supplement.
2. Fever, headache, common cold, nausea, and nosebleed are some common symptoms, which were observed in a study when healthy individuals were treated with garcinia cambogia extract powder. If there are any symptoms or side effects, immediately stop taking garcinia cambogia supplement and seek medical advice.
3. Maintain a huge time gap (minimum 3 hours gap) between garcinia cambogia supplements and other drugs.

Summary

In summary, it can be stated that garcinia cambogia is effective in reducing body weight and body fat. Besides this it is also effective is lowering the level of plasma glucose level, cholesterol level as well as triglyceride levels. Treatment with garcinia cambogia combats oxidative stress and drops the level of inflammation. All these benefits of garcinia cambogia are due to the presence of an active compound in it called ‘hydroxycitric acid’.

Sources:

source1-https://www.ayurtimes.com/garcinia-cambogia-garcinia-gummi-gutta-kudampuli-malabar-tamarind/

source 2-https://www.healthline.com/health/food-nutrition/things-you-didnt-know-about-garcinia-cambogia#6

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